Quantitative Proteomics Analysis of the Effects of Ionizing Radiation in Wild Type and p53(K317R) Knock-in Mouse Thymocytes

The tumor suppressor protein p53 is a sequence-specific transcription factor that has crucial roles in apoptosis, cell cycle arrest, cellular senescence, and DNA repair. Following exposure to a variety of stresses, p53 becomes post-translationally modified with concomitant increases in activity and...

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Bibliographische Detailangaben
Hauptverfasser: Miller Jenkins, Lisa M., Mazur, Sharlyn J., Rossi, Matteo, Gaidarenko, Olga, Xu, Yang, Appella, Ettore
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Special Issue: 8th International Symposium on Mass Spectrometry in the Life Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2401331/
https://ncbi.nlm.nih.gov/pubmed/18178582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700482-MCP200
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