Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

Posttranslational modifications of p53, including phosphorylation and acetylation, play important roles in regulating p53 stability and activity. Mouse p53 is acetylated at lysine 317 by PCAF and at multiple lysine residues at the extreme carboxyl terminus by CBP/p300 in response to genotoxic and so...

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Autori principali: Chao, Connie, Wu, Zhiqun, Mazur, Sharlyn J., Borges, Helena, Rossi, Matteo, Lin, Tongxiang, Wang, Jean Y. J., Anderson, Carl W., Appella, Ettore, Xu, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592865/
https://ncbi.nlm.nih.gov/pubmed/16943427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00062-06
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