Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

Posttranslational modifications of p53, including phosphorylation and acetylation, play important roles in regulating p53 stability and activity. Mouse p53 is acetylated at lysine 317 by PCAF and at multiple lysine residues at the extreme carboxyl terminus by CBP/p300 in response to genotoxic and so...

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Main Authors: Chao, Connie, Wu, Zhiqun, Mazur, Sharlyn J., Borges, Helena, Rossi, Matteo, Lin, Tongxiang, Wang, Jean Y. J., Anderson, Carl W., Appella, Ettore, Xu, Yang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592865/
https://ncbi.nlm.nih.gov/pubmed/16943427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00062-06
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