Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

Posttranslational modifications of p53, including phosphorylation and acetylation, play important roles in regulating p53 stability and activity. Mouse p53 is acetylated at lysine 317 by PCAF and at multiple lysine residues at the extreme carboxyl terminus by CBP/p300 in response to genotoxic and so...

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Bibliographische Detailangaben
Hauptverfasser: Chao, Connie, Wu, Zhiqun, Mazur, Sharlyn J., Borges, Helena, Rossi, Matteo, Lin, Tongxiang, Wang, Jean Y. J., Anderson, Carl W., Appella, Ettore, Xu, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592865/
https://ncbi.nlm.nih.gov/pubmed/16943427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00062-06
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