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In Vitro Activation of the IκB Kinase Complex by Human T-cell Leukemia Virus Type-1 Tax
Human T-cell leukemia virus type-I expresses Tax, a 40-kDa oncoprotein that activates IκB kinase (IKK), resulting in constitutive activation of NFκB. Herein, we have developed an in vitro signaling assay to analyze IKK complex activation by recombinant Tax. Using this assay in combination with repor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2397464/ https://ncbi.nlm.nih.gov/pubmed/18223255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704831200 |
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