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Regulation of IκB Kinase Complex by Phosphorylation of γ-Binding Domain of IκB Kinase β by Polo-like Kinase 1
IκB kinase (IKK) complex is a key regulator of NF-κB pathways. Signal-induced interaction of the IKKγ (NEMO) subunit with the C-terminal IKKγ/NEMO-binding domain (γBD) of IKKβ is an essential interaction for IKK regulation. Underlying regulatory mechanism(s) of this interaction are not known. Phosph...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602907/ https://ncbi.nlm.nih.gov/pubmed/18957422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806258200 |
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