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Phosphorylation and Stabilization of TAp63γ by IκB Kinase-β
Post-translational modification of the p53 family members is key to their regulation. Here we report the phosphorylation of TAp63γ, but not ΔNp63γ, by IκB kinase β (IKKβ). Activation of IKKβ by γ radiation or tumor necrosis factor-α led to increased TAp63γ protein levels in cells. IKKβ, but not its...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2414271/ https://ncbi.nlm.nih.gov/pubmed/18411264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801394200 |
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