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Phosphorylation and Stabilization of TAp63γ by IκB Kinase-β

Post-translational modification of the p53 family members is key to their regulation. Here we report the phosphorylation of TAp63γ, but not ΔNp63γ, by IκB kinase β (IKKβ). Activation of IKKβ by γ radiation or tumor necrosis factor-α led to increased TAp63γ protein levels in cells. IKKβ, but not its...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: MacPartlin, Mary, Zeng, Shelya X., Lu, Hua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414271/
https://ncbi.nlm.nih.gov/pubmed/18411264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801394200
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