GSK-3 Phosphorylates δ-Catenin and Negatively Regulates Its Stability via Ubiquitination/Proteosome-mediated Proteolysis

δ-Catenin was first identified because of its interaction with presenilin-1, and its aberrant expression has been reported in various human tumors and in patients with Cri-du-Chat syndrome, a form of mental retardation. However, the mechanism whereby δ-catenin is regulated in cells has not been full...

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Hlavní autoři: Oh, Minsoo, Kim, Hangun, Yang, Ilhwan, Park, Ja-Hye, Cong, Wei-Tao, Baek, Moon-Chang, Bareiss, Sonja, Ki, Hyunkyoung, Lu, Qun, No, Jinhyung, Kwon, Inho, Choi, Jung-Kap, Kim, Kwonseop
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Protein Synthesis, Post-Translational Modification, and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781401/
https://ncbi.nlm.nih.gov/pubmed/19706605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002659
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