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Tyrosine Phosphorylation Is Required for IκB Kinase-β (IKKβ) Activation and Function in Osteoclastogenesis

The transcription factor NF-κB is crucial for numerous cellular functions such as survival, differentiation, immunity, and inflammation. A key function of this family of transcription factors is regulation of osteoclast differentiation and function, which in turn controls skeletal homeostasis. The I...

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Detalhes bibliográficos
Main Authors: Darwech, Isra, Otero, Jesse E., Alhawagri, Muhammad A., Abu-Amer, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919116/
https://ncbi.nlm.nih.gov/pubmed/20534585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121533
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