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Structural Requirements for Yersinia YopJ Inhibition of MAP Kinase Pathways
MAPK signaling cascades are evolutionally conserved. The bacterial effector, YopJ, uses the unique activity of Ser/Thr acetylation to inhibit the activation of the MAPK kinase (MKK) and prevent activation by phosphorylation. YopJ is also able to block yeast MAPK signaling pathways using this mechani...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2147050/ https://ncbi.nlm.nih.gov/pubmed/18167536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001375 |
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