A carregar...
Noonan Syndrome-associated SHP-2/Ptpn11 Mutants Enhance SIRPα and PZR Tyrosyl Phosphorylation and Promote Adhesion-mediated ERK Activation
Noonan syndrome (NS) is an autosomal dominant disorder that is associated with multiple developmental abnormalities. Activated mutations of the protein-tyrosine phosphatase, SHP-2/PTPN11, have been reported in ∼50% of NS cases. Despite being activated, NS-associated SHP-2 mutants require plasma memb...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2397460/ https://ncbi.nlm.nih.gov/pubmed/18378677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801382200 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|