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DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy•dG
Bypass of the configurationally stable analogue (β-C-Fapy•dG) of the formamidopyrimidine lesion derived from 2'-deoxyguanosine oxidation (Fapy•dG) was studied in vitro and in E. coli. The exonuclease deficient Klenow fragment of E. coli DNA polymerase I (Klenow exo¯) misincorporated dA most fre...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396951/ https://ncbi.nlm.nih.gov/pubmed/18242999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.01.025 |
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