DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy•dG

Bypass of the configurationally stable analogue (β-C-Fapy•dG) of the formamidopyrimidine lesion derived from 2'-deoxyguanosine oxidation (Fapy•dG) was studied in vitro and in E. coli. The exonuclease deficient Klenow fragment of E. coli DNA polymerase I (Klenow exo¯) misincorporated dA most fre...

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Bibliografiske detaljer
Main Authors:	Weledji, Yvonne N., Wiederholt, Carissa J., Delaney, Michael O., Greenberg, Marc M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2008
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2396951/ https://ncbi.nlm.nih.gov/pubmed/18242999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.01.025
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DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy•dG

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