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Latent TGF-β1 Protects Against Crescentic Glomerulonephritis

Despite the critical role that TGF-β plays in renal fibrosis, transgenic mice that overexpress human latent TGF-β1 in the skin exhibit normal renal histology and function even though circulating levels of latent TGF-β1 are an order of magnitude higher than wild-type animals. In fact, latent TGF-β1 s...

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Autori principali: Huang, Xiao R., Chung, Arthur C.K., Zhou, Li, Wang, Xiao J., Lan, Hui Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396747/
https://ncbi.nlm.nih.gov/pubmed/18216320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007040484
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