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The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

Regulatory T cells (Tregs) have been shown to play a protective role in glomerulonephritis (GN) and Foxp3 is a master transcription factor in Treg development. In this study, we examined the functional role and mechanisms of Foxp3 in a mouse model of accelerated anti-glomerular basement membrane (an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Chen, Huang, Xiao-Ru, Fung, Erik, Liu, Hua-Feng, Lan, Hui-Yao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431186/
https://ncbi.nlm.nih.gov/pubmed/28469165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01515-8
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