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The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis
Regulatory T cells (Tregs) have been shown to play a protective role in glomerulonephritis (GN) and Foxp3 is a master transcription factor in Treg development. In this study, we examined the functional role and mechanisms of Foxp3 in a mouse model of accelerated anti-glomerular basement membrane (an...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431186/ https://ncbi.nlm.nih.gov/pubmed/28469165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01515-8 |
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