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Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

The inhalation of airborne pollutants, such as asbestos or silica, is linked to inflammation of the lung, fibrosis, and lung cancer. How the presence of pathogenic dust is recognized and how chronic inflammatory diseases are triggered are poorly understood. Here, we show that asbestos and silica are...

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Detalhes bibliográficos
Main Authors: Dostert, Catherine, Pétrilli, Virginie, Van Bruggen, Robin, Steele, Chad, Mossman, Brooke T, Tschopp, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396588/
https://ncbi.nlm.nih.gov/pubmed/18403674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1156995
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