The NALP3 inflammasome is involved in the innate immune response to amyloid-β

The fibrillar peptide amyloid-β (Aβ) has a chief function in the pathogenesis of Alzheimer’s disease. Interleukin 1β (IL-1β) is a key cytokine in the inflammatory response to Aβ. Insoluble materials such as crystals activate the inflammasome formed by the cytoplasmic receptor NALP3, which results in...

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Detaylı Bibliyografya
Asıl Yazarlar: Halle, Annett, Hornung, Veit, Petzold, Gabor C, Stewart, Cameron R, Monks, Brian G, Reinheckel, Thomas, Fitzgerald, Katherine A, Latz, Eicke, Moore, Kathryn J, Golenbock, Douglas T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101478/
https://ncbi.nlm.nih.gov/pubmed/18604209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1636
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