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iGLuc: a luciferase-based inflammasome and protease activity reporter
Measurement of protease activity in living cells or organisms remains a challenging task. We here present a transgene-encoded biosensor that reports the proteolytic activity of caspase-1 in the course of inflammasome activation and that of other proteases in a highly sensitive and specific manner. T...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127477/ https://ncbi.nlm.nih.gov/pubmed/23291722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2327 |
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