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Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
BACKGROUND: Characteristic symptoms of malaria include recurrent fever attacks and neurodegeneration, signs that are also found in patients with a hyperactive Nalp3 inflammasome. Plasmodium species produce a crystal called hemozoin that is generated by detoxification of heme after hemoglobin degrada...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714977/ https://ncbi.nlm.nih.gov/pubmed/19652710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006510 |
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