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Biological function in a non-native partially folded state of a protein

As structural flexibility is known to be required for enzyme catalysis and pattern recognition and a significant fraction of eukaryotic proteins appear to be unfolded or contain unstructured regions, biological activity of conformational states distinct from fully folded structures could be more com...

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Detalhes bibliográficos
Main Authors: Bemporad, Francesco, Gsponer, Joerg, Hopearuoho, Harri I, Plakoutsi, Georgia, Stati, Gianmarco, Stefani, Massimo, Taddei, Niccolò, Vendruscolo, Michele, Chiti, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396399/
https://ncbi.nlm.nih.gov/pubmed/18451804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.82
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