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High-Level Folate Production in Fermented Foods by the B(12) Producer Lactobacillus reuteri JCM1112

We observed that Lactobacillus reuteri JCM1112 produces B(12) and folate. However, the folate/B(12) mass ratio found was far below that desired for human consumption (∼170:1). We used metabolic engineering applying genetic and physiological approaches to improve this ratio and developed a generic an...

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Detalhes bibliográficos
Main Authors: Santos, Filipe, Wegkamp, Arno, de Vos, Willem M., Smid, Eddy J., Hugenholtz, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394963/
https://ncbi.nlm.nih.gov/pubmed/18344331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02719-07
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