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Structures of the rare-cutting restriction endonuclease NotI reveal a novel metal binding fold involved in DNA recognition
The structure of the rare-cutting restriction endonuclease NotI, which recognizes the 8 basepair target 5′-GCGGCCGC-3′, has been solved with and without bound DNA. Because of its specificity (recognizing a site that occurs once per 65kb), NotI is used to generate large genomic fragments and to map D...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390919/ https://ncbi.nlm.nih.gov/pubmed/18400177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.01.017 |
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