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Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI
The crystal structure of the rare-cutting HNH restriction endonuclease PacI in complex with its eight base pair target recognition sequence 5'-TTAATTAA-3' has been determined to 1.9 Å resolution. The enzyme forms an extended homodimer, with each subunit containing two zinc-bound motifs sur...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886031/ https://ncbi.nlm.nih.gov/pubmed/20541511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.03.009 |
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