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Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI

BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5′-CCTCAGC-3′, generating 3-base, 5′-overhangs. BbvCI is composed of two protein subunits, each containing one catalytic site. Either site can be inactivated by mutation resulting in enzyme variants that...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Shen, Betty W, Doyle, Lindsey, Bradley, Phil, Heiter, Daniel F, Lunnen, Keith D, Wilson, Geoffrey G, Stoddard, Barry L
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326814/
https://ncbi.nlm.nih.gov/pubmed/30395313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1059
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