Generation of deletion mutants of simian immunodeficiency virus incapable of proviral integration.

Deletion mutants of simian immunodeficiency virus (SIVmac) which were unable to integrate into host cells were generated by removing a portion of the integrase (IN) domain of the pol gene. The resulting plasmid was transfected into HUT-78 and human rhabdomyosarcoma cells. In comparison with the pare...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Prakash, K, Ranganathan, P N, Mettus, R, Reddy, P, Srinivasan, A, Plotkin, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238272/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1727479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.1.167-171.1992
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