Generation of deletion mutants of simian immunodeficiency virus incapable of proviral integration.

Deletion mutants of simian immunodeficiency virus (SIVmac) which were unable to integrate into host cells were generated by removing a portion of the integrase (IN) domain of the pol gene. The resulting plasmid was transfected into HUT-78 and human rhabdomyosarcoma cells. In comparison with the pare...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Prakash, K, Ranganathan, P N, Mettus, R, Reddy, P, Srinivasan, A, Plotkin, S
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1992
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238272/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1727479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.1.167-171.1992
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