Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

Twelve rhesus monkeys were vaccinated with SIVmac316 delta nef (lacking nef sequences), and 12 were vaccinated with SIVmac239 delta3 (lacking nef, vpr, and upstream sequences in U3). SIVmac316 and SIVmac239 differ by only eight amino acids in the envelope; these changes render SIVmac316 highly compe...

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Библиографические подробности
Главные авторы: Wyand, M S, Manson, K H, Garcia-Moll, M, Montefiori, D, Desrosiers, R C
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC190248/
https://ncbi.nlm.nih.gov/pubmed/8648707
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