Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

Twelve rhesus monkeys were vaccinated with SIVmac316 delta nef (lacking nef sequences), and 12 were vaccinated with SIVmac239 delta3 (lacking nef, vpr, and upstream sequences in U3). SIVmac316 and SIVmac239 differ by only eight amino acids in the envelope; these changes render SIVmac316 highly compe...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Wyand, M S, Manson, K H, Garcia-Moll, M, Montefiori, D, Desrosiers, R C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3724-3733.1996
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