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Biochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigen.

The role of the origin-binding domain of simian virus 40 large tumor antigen (T antigen) in the initiation of virus DNA replication was investigated by analyzing the biochemical activities of a series of mutants with single-site substitutions in this region. These activities include origin-specific...

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Autors principals: Simmons, D T, Upson, R, Wun-Kim, K, Young, W
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC237792/
https://ncbi.nlm.nih.gov/pubmed/8389924
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