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Biochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigen.

The role of the origin-binding domain of simian virus 40 large tumor antigen (T antigen) in the initiation of virus DNA replication was investigated by analyzing the biochemical activities of a series of mutants with single-site substitutions in this region. These activities include origin-specific...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Simmons, D T, Upson, R, Wun-Kim, K, Young, W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.4227-4236.1993
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