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Biochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigen.

The role of the origin-binding domain of simian virus 40 large tumor antigen (T antigen) in the initiation of virus DNA replication was investigated by analyzing the biochemical activities of a series of mutants with single-site substitutions in this region. These activities include origin-specific...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Simmons, D T, Upson, R, Wun-Kim, K, Young, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.7.4227-4236.1993
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