CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection

Inactivations of DNA repair genes, O(6)-methylguanine-DNA methyltransferase (MGMT) and hMLH1, by promoter hypermethylation have been reported in several types of primary human neoplasia. This epigenetic inactivation mechanism remains elusive in hepatocellular carcinoma (HCC). To investigate the rela...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Matsukura, S, Soejima, H, Nakagawachi, T, Yakushiji, H, Ogawa, A, Fukuhara, M, Miyazaki, K, Nakabeppu, Y, Sekiguchi, M, Mukai, T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2003
Gaiak:
Molecular and Cellular Pathology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377174/
https://ncbi.nlm.nih.gov/pubmed/12592365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600743
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