Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma

Colorectal cancer (CRC) is the third most common cancer in men and the second in women worldwide. CRC development is the result of genetic and epigenetic alterations accumulation in the epithelial cells of colon mucosa. In the present study, DNA methylation, an epigenetic event, was evaluated in tum...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Michailidi, Christina, Theocharis, Stamatios, Tsourouflis, Gerasimos, Pletsa, Vasiliki, Kouraklis, Gregorios, Patsouris, Efstratios, Papavassiliou, Athanasios G, Troungos, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935349/
https://ncbi.nlm.nih.gov/pubmed/25908636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215583800
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