Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma

Colorectal cancer (CRC) is the third most common cancer in men and the second in women worldwide. CRC development is the result of genetic and epigenetic alterations accumulation in the epithelial cells of colon mucosa. In the present study, DNA methylation, an epigenetic event, was evaluated in tum...

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Vydáno v:Exp Biol Med (Maywood)
Hlavní autoři: Michailidi, Christina, Theocharis, Stamatios, Tsourouflis, Gerasimos, Pletsa, Vasiliki, Kouraklis, Gregorios, Patsouris, Efstratios, Papavassiliou, Athanasios G, Troungos, Constantinos
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935349/
https://ncbi.nlm.nih.gov/pubmed/25908636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215583800
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