Histone deacetylase (HDAC)-1, −2, −4 and −6 expression in human pancreatic adenocarcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients’ survival

BACKGROUND: Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The present study aimed to evaluate the clinical significance of HDAC-1, −2, −4 an...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Gastroenterol
Auteurs principaux: Giaginis, Constantinos, Damaskos, Christos, Koutsounas, Ioannis, Zizi-Serbetzoglou, Adamantia, Tsoukalas, Nicolaos, Patsouris, Efstratios, Kouraklis, Gregorios, Theocharis, Stamatios
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621854/
https://ncbi.nlm.nih.gov/pubmed/26502922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0379-y
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