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Tumour targeting of humanised cross-linked divalent-fab′ antibody fragments: a clinical phase I/II study
Antibody engineering has made it possible to design antibodies with optimal characteristics for delivery of radionuclides for tumour imaging and therapy. A humanised divalent-Fab′ cross-linked with a bis-maleimide linker referred to as humanised divalent-Fab′ maleimide was produced as a result of th...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375360/ https://ncbi.nlm.nih.gov/pubmed/11986771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600198 |
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