Dosimetric evaluation and radioimmunotherapy of anti-tumour multivalent Fab́ fragments

We have been investigating the use of cross-linked divalent (DFM) and trivalent (TFM) versions of the anti-carcinoembryonic antigen (CEA) monoclonal antibody A5B7 as possible alternatives to the parent forms (IgG and F(ab́)(2)) which have been used previously in clinical radioimmunotherapy (RIT) stu...

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Hlavní autoři: Casey, J L, Pedley, R B, King, D J, Green, A J, Yarranton, G T, Begent, R H J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1999
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362943/
https://ncbi.nlm.nih.gov/pubmed/10576653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690795
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