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Fractionated (131)I anti-CEA radioimmunotherapy: effects on xenograft tumour growth and haematological toxicity in mice

Dose fractionation has been proposed as a method to improve the therapeutic ratio of radioimmunotherapy (RIT). This study compared a single administration of 7.4 MBq (131)I-anti-CEA antibody given on day 1 with the same total activity given as fractionated treatment: 3.7 MBq (days 1 and 3), 2.4 MBq...

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Detalhes bibliográficos
Main Authors: Violet, J A, Dearling, J L J, Green, A J, Begent, R H J, Pedley, R B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527834/
https://ncbi.nlm.nih.gov/pubmed/18682714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604511
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