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Deletion of Histone Deacetylase 3 reveals critical roles in S-phase progression and DNA damage control
Histone deacetylases (HDAC) are enzymes that modify key residues in histones to regulate chromatin architecture, and play a vital role in cell survival, cell cycle progression, and tumorigenesis. To understand the function of Hdac3, a critical component of the N-CoR/SMRT repression complex, a condit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373760/ https://ncbi.nlm.nih.gov/pubmed/18406327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.02.030 |
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