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Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
Histone deacetylase 3 (Hdac3) is an enzymatic component of transcriptional repression complexes recruited by the nuclear hormone receptors. Inactivation of Hdac3 in cancer cell lines triggered apoptosis, and removal of Hdac3 in the germ line of mice caused embryonic lethality. Therefore, we deleted...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323257/ https://ncbi.nlm.nih.gov/pubmed/18354499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.51 |
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