Loading...

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

Histone deacetylase 3 (Hdac3) is an enzymatic component of transcriptional repression complexes recruited by the nuclear hormone receptors. Inactivation of Hdac3 in cancer cell lines triggered apoptosis, and removal of Hdac3 in the germ line of mice caused embryonic lethality. Therefore, we deleted...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Knutson, Sarah K, Chyla, Brenda J, Amann, Joseph M, Bhaskara, Srividya, Huppert, Stacey S, Hiebert, Scott W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323257/
https://ncbi.nlm.nih.gov/pubmed/18354499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.51
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!