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Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression

BACKGROUND: Histone deacetylases (HDACs) play a critical role in the maintenance of genome stability. Class I HDACs, histone deacetylase 1 and 2 (Hdac1 and Hdac2) are recruited to the replication fork by virtue of their interactions with the replication machinery. However, functions for Hdac1 and Hd...

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Detalhes bibliográficos
Main Authors: Bhaskara, Srividya, Jacques, Vincent, Rusche, James R, Olson, Eric N, Cairns, Bradley R, Chandrasekharan, Mahesh B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765969/
https://ncbi.nlm.nih.gov/pubmed/23947532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-27
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