Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma

Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored as anti-cancer agents. In fact, two histone deacetylase inhibitors (HDIs), SA...

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Detalhes bibliográficos
Main Authors: Wells, Christina E., Bhaskara, Srividya, Stengel, Kristy R., Zhao, Yue, Sirbu, Bianca, Chagot, Benjamin, Cortez, David, Khabele, Dineo, Chazin, Walter J., Cooper, Andrew, Jacques, Vincent, Rusche, James, Eischen, Christine M., McGirt, Laura Y., Hiebert, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718806/
https://ncbi.nlm.nih.gov/pubmed/23894374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068915
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