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The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
Epithelial ovarian cancer remains the deadliest gynecologic malignancy. Despite advances in treatment, new approaches are needed. Histone deacetylases (HDACs) are a family of enzymes that regulate gene expression by removing acetyl groups from lysine residues on histones and non-histone proteins. In...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033132/ https://ncbi.nlm.nih.gov/pubmed/24904826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00111 |
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