Preclinical studies on histone deacetylase inhibitors as therapeutic reagents for endometrial and ovarian cancers

Histone deacetylases (HDACs) remove acetyl groups from lysine residues of histones and the deacetylation allows for tighter electrostatic interactions between DNA and histones, leading to a more compact chromatin conformation with limited access for transactivators and the suppression of transcripti...

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Detaylı Bibliyografya
Asıl Yazarlar: Singh, Brahma N, Zhou, Hongyuan, Li, Jinping, Tipton, Tracy, Wang, Bin, Shao, Guo, Gilbert, E Nickolas, Li, Qiang, Jiang, Shi-Wen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273414/
https://ncbi.nlm.nih.gov/pubmed/22112317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.11.124
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