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Expression of Class I Histone Deacetylases Indicates Poor Prognosis in Endometrioid Subtypes of Ovarian and Endometrial Carcinomas

Histone deacetylase (HDAC) inhibitors are an emerging class of targeted cancer therapeutics, and little is known about HDAC expression in gynecologic malignancies. Therefore, we tested the hypothesis whether high-level expression of class 1 HDACs (HDAC1, 2, and 3) is associated with clinically disti...

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Autori principali: Weichert, Wilko, Denkert, Carsten, Noske, Aurelia, Darb-Esfahani, Silvia, Dietel, Manfred, Kalloger, Steve E, Huntsman, David G, Köbel, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517648/
https://ncbi.nlm.nih.gov/pubmed/18714364
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