Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression

BACKGROUND: In breast cancer, the role of epigenetic alterations including modifications of the acetylation status of histones in carcinogenesis has been an important research focus during the last years. An increased deacetylation of histones leads to increased cell proliferation, cell migration, a...

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Detalhes bibliográficos
Main Authors: Müller, Berit Maria, Jana, Lisa, Kasajima, Atsuko, Lehmann, Annika, Prinzler, Judith, Budczies, Jan, Winzer, Klaus-Jürgen, Dietel, Manfred, Weichert, Wilko, Denkert, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646665/
https://ncbi.nlm.nih.gov/pubmed/23627572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-215
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