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Fast-folding protein kinetics, hidden intermediates, and the sequential stabilization model

Do two-state proteins fold by pathways or funnels? Native-state hydrogen exchange experiments show discrete nonnative structures in equilibrium with the native state. These could be called hidden intermediates (HI) because their populations are small at equilibrium, and they are not detected in kine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ozkan, S. Banu, Dill, Ken A., Bahar, Ivet
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373683/
https://ncbi.nlm.nih.gov/pubmed/12142450
Tagiau: Ychwanegu Tag
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