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Fast-folding protein kinetics, hidden intermediates, and the sequential stabilization model

Do two-state proteins fold by pathways or funnels? Native-state hydrogen exchange experiments show discrete nonnative structures in equilibrium with the native state. These could be called hidden intermediates (HI) because their populations are small at equilibrium, and they are not detected in kine...

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Hlavní autoři: Ozkan, S. Banu, Dill, Ken A., Bahar, Ivet
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373683/
https://ncbi.nlm.nih.gov/pubmed/12142450
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