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Protein folding by zipping and assembly

How do proteins fold so quickly? Some denatured proteins fold to their native structures in only microseconds, on average, implying that there is a folding “mechanism,” i.e., a particular set of events by which the protein short-circuits a broader conformational search. Predicting protein structures...

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Autors principals: Ozkan, S. Banu, Wu, G. Albert, Chodera, John D., Dill, Ken A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924571/
https://ncbi.nlm.nih.gov/pubmed/17620603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703700104
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