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Transmembrane signal transduction of the α(IIb)β(3) integrin

Integrins are composed of noncovalently bound dimers of an α- and a β-subunit. They play an important role in cell-matrix adhesion and signal transduction through the cell membrane. Signal transduction can be initiated by the binding of intracellular proteins to the integrin. Binding leads to a majo...

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Detalles Bibliográficos
Main Authors: Gottschalk, Kay E., Adams, Paul D., Brunger, Axel T., Kessler, Horst
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373644/
https://ncbi.nlm.nih.gov/pubmed/12070332
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